Tokyo, June 19 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061954) titled 'An Observational Study of Lower Limb Muscle Strength and Changes in Force Generation in Patients With Parkinson's Disease and Related Disorders' on June 19.

Study Type: Observational

Primary Sponsor: Institute - Juntendo University Urayasu Hospital

Condition: Condition - Parkinson's Disease, Multiple System Atrophy, Supranuclear Palsy, Progressive Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The aim of this study is to quantitatively evaluate lower limb muscle strength and changes in force generation during repeated muscle contractions in patients with Parkinson's disease and related disorders, and to explore their associations with motor function, disease severity, and clinical characteristics. Basic objectives2 - Others

Eligibility: Age-lower limit - 20 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - 1. Patients aged 20 years or older at the time of providing informed consent. 2. Patients clinically diagnosed with Parkinson's disease or a related disorder, including multiple system atrophy or progressive supranuclear palsy. 3. Patients with Hoehn and Yahr stage 1-4 disease. 4. Patients who have received a sufficient explanation of the study, fully understood its contents, and provided written informed consent to participate of their own free will. Key exclusion criteria - 1. Patients with comorbidities that may reduce muscle strength, such as orthopedic, psychiatric, or other neurological disorders. 2. Patients in whom muscle strength cannot be reliably assessed because of severe dyskinesia. 3. Patients who are considered unsuitable for participation in the study by the principal investigator for any other reason. Target Size - 34

Recruitment Status: Recruitment status - Open public recruiting Date of protocol fixation - 2025 Year 05 Month 10 Day Date of IRB - 2025 Year 06 Month 30 Day Anticipated trial start date - 2025 Year 07 Month 03 Day Last follow-up date - 2028 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000070891

Disclaimer: Curated by HT Syndication.