Tokyo, Oct. 21 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000059469) titled 'A Study on the Effect of the White Coat Effect on Adrenaline Induced Blood Pressure Elevation' on Oct. 21.

Study Type: Observational

Primary Sponsor: Institute - KANAGAWA DENTAL UNIVERSITY

Condition: Condition - Dental Anesthesiology Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The primary objective of this study is to quantitatively compare and evaluate the effect of the white coat effect on the blood pressure increase caused by epinephrine-added local anesthetics, thereby verifying the safety of epinephrine-added local anesthetics in patients with the white coat effect. Basic objectives2 - Others

Eligibility: Age-lower limit - 20 years-old

Gender - Male and Female Key inclusion criteria - Patients undergoing dental treatment requiring local anesthesia Key exclusion criteria - Severe cardiovascular disease (unstable angina, myocardial infarction within the past 6 months, severe heart failure (NYHA class III/IV), severe arrhythmia) Blood pressure-related disorders (secondary hypertension, severe hypertension ) Drug-related (Contraindications to epinephrine-containing lidocaine hydrochloride preparations, use of beta-blockers) Pharmacologically assisted behavioral modification (Psychotropic sedation, general anesthesia) Other (Pregnancy or lactation, contraindications to upper arm blood pressure measurement, difficulty cooperating due to dementia, psychiatric disorders, intellectual disability, etc. Deemed inappropriate by the principal investigator) Target Size - 100

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2025 Year 07 Month 24 Day Date of IRB - 2025 Year 07 Month 24 Day Anticipated trial start date - 2025 Year 10 Month 21 Day Last follow-up date - 2027 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068014

Disclaimer: Curated by HT Syndication.