Tokyo, Aug. 17 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062448) titled 'A Comparison of the Incidence of Postdischarge Nausea and Vomiting' on Aug. 17.
Study Type:
Interventional
Study Design:
Basic Design - Parallel
Randomization - Randomized
Blinding - Single blind -participants are blinded
Control - Active
Primary Sponsor:
Institute - Hiroshima University
Condition:
Condition - Same-Day Surgery for the Nose and Sinuses
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - To determine whether there is a difference in the incidence of PDNV between total intravenous anesthesia using remimazolam and inhalation anesthesia using sevoflurane in same-day nasal and sinus surgeries.
Basic objectives2 - Safety
Intervention:
Interventions/Control_1 - Remimazolam TIVA anesthesia
Interventions/Control_2 - sevoflurane anesthesia
Eligibility:
Age-lower limit - 20
years-old
<=
Age-upper limit - Not applicable
Gender - Male and Female
Key inclusion criteria - Patients undergoing same-day nasal and sinus surgery
Adults classified as ASA I or II
Key exclusion criteria - Patients who are pregnant or breastfeeding, or who may be pregnant or breastfeeding
Patients with allergies to benzodiazepines or volatile anesthetics
Patients whose condition is difficult to assess due to cognitive impairment or other factors
Emergency surgical cases
Patients Using Steroids
Target Size - 80
Recruitment Status:
Recruitment status - Preinitiation
Date of protocol fixation - 2026 Year 08 Month 02 Day
Anticipated trial start date - 2026 Year 08 Month 24 Day
Last follow-up date - 2027 Year 03 Month 31 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000071364
Disclaimer: Curated by HT Syndication.
