Tokyo, May 11 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061479) titled 'A Comprehensive MRI Evaluation of Structural and Physiological Changes in Lower Leg Tissue Associated with Compression from Compression Stockings' on May 11.

Study Type: Interventional

Study Design: Basic Design - Single arm Randomization - Non-randomized Blinding - Open -no one is blinded Control - Self control

Primary Sponsor: Institute - Fukushima Medical University

Condition: Condition - Healthy volunteer Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The purpose of this study is to evaluate structural and physiological changes in the skin, subcutaneous tissue, and skeletal muscle of the lower leg before and after wearing compression stockings in healthy volunteer, using quantitative MRI measures. Basic objectives2 - Others

Intervention: Interventions/Control_1 - Putting on compression stockings

Eligibility: Age-lower limit - 18 years-old = Gender - Male and Female Key inclusion criteria - 1. Individuals aged 18 to 35 at the time of consent 2. Individuals without obvious edema, skin conditions, or injuries on the lower legs 3. Individuals capable of wearing compression stockings 4. Individuals who consent to undergoing an MRI examination and for whom safety during the MRI examination can be ensured Key exclusion criteria - 1. Individuals with metal devices or other foreign objects in their bodies due to past surgeries, or those for whom an MRI scan is difficult due to conditions such as claustrophobia 2. Individuals with deep vein thrombosis in the lower limbs, severe peripheral arterial disease, or conditions for which compression therapy is contraindicated 3. Pregnant women or women who may be pregnant 4. Individuals deemed unsuitable by the principal investigator 5. Individuals who have withdrawn their consent to participate in this study Target Size - 40

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2026 Year 05 Month 11 Day Anticipated trial start date - 2026 Year 05 Month 11 Day Last follow-up date - 2029 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000070347

Disclaimer: Curated by HT Syndication.