Tokyo, June 22 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061992) titled 'Multicenter Study on the Effects of Body Position on Exercise Capacity in Patients with Idiopathic Pleuroparenchymal Fibroelastosis (PPFE)' on June 22.

Study Type: Observational

Primary Sponsor: Institute - Kindai University

Condition: Condition - Idiopathic Pleuroparenchymal Fibroelastosis (PPFE) Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The primary objective of this study is to determine the differences in exercise capacity and ventilatory efficiency between sitting and supine positions in patients with idiopathic pleuroparenchymal fibroelastosis (PPFE). In addition, this study aims to evaluate the effectiveness of the Gravity Release Intervention Technique (GRIT) and to identify factors associated with its therapeutic effects. Basic objectives2 - Efficacy

Eligibility: Age-lower limit - 20 years-old = Gender - Male and Female Key inclusion criteria - 1.Patients diagnosed with idiopathic pleuroparenchymal fibroelastosis (iPPFE), chronic obstructive pulmonary disease (COPD), or idiopathic pulmonary fibrosis (IPF), whose clinical condition has been stable for at least 4 weeks, or healthy adults. 2.Patients with a modified Medical Research Council (mMRC) dyspnea score >1. 3.Written informed consent obtained prior to participation. Key exclusion criteria - 1.Pneumothorax within 3 months before enrollment. 2.Receiving long term oxygen therapy. 3.Musculoskeletal disorders affecting upper or lower limb muscle strength. 4.Connective tissue diseases interfering with physical function assessment. 5.Cerebrovascular disease with clinically significant neurological deficits. 6.6. Ongoing pulmonary rehabilitation at enrollment (completion at least 6 months before enrollment is allowed). 7.Any condition judged by the investigator to make participation inappropriate. Target Size - 90

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2025 Year 11 Month 25 Day Anticipated trial start date - 2026 Year 06 Month 18 Day Last follow-up date - 2029 Year 12 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000070940

Disclaimer: Curated by HT Syndication.