Tokyo, May 11 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061459) titled 'A Prospective Clinical Study on the Utility of EUS-guided Fine-Needle Aspiration for Right Hepatic Lobe Lesions' on May 11.
Study Type:
Interventional
Study Design:
Basic Design - Single arm
Randomization - Non-randomized
Blinding - Open -no one is blinded
Control - Uncontrolled
Primary Sponsor:
Institute - Aichi Cancer Center
Condition:
Condition - Right Hepatic Lobe Lesions
Classification by malignancy - Malignancy
Genomic information - NO
Objective:
Narrative objectives1 - To prospectively evaluate the diagnostic performance, technical success rate, and safety of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) for right hepatic lobe lesions.
Basic objectives2 - Safety,Efficacy
Intervention:
Interventions/Control_1 - EUS-FNA
Eligibility:
Age-lower limit - Not applicable
Age-upper limit - Not applicable
Gender - Male and Female
Key inclusion criteria - 1) Adequate major organ function (bone marrow, cardiac, hepatic, pulmonary, and renal function) is preserved.
2) Patients with a performance status suitable for endoscopy: ECOG Performance Status 0, 1, or 2.
3) Patients expected to survive for at least 4 weeks.
4) Written informed consent has been obtained from the patient.
Key exclusion criteria - 1) Patients with a history of surgical resection of the right hepatic lobe.
2) Patients at high risk of bleeding:
Platelet count = 1.5
APTT >= 1.5 times the upper limit of normal
3) Patients with gastrointestinal stenosis.
4) Patients with massive ascites in whom a safe puncture route cannot be secured.
5) Patients with active infection or uncontrolled cholangitis or sepsis.
6) Patients in whom the operator judges that lesion visualization or a safe puncture route cannot be achieved by EUS.
7) Patients deemed inappropriate for this study by the attending physician.
Target Size - 80
Recruitment Status:
Recruitment status - Preinitiation
Date of protocol fixation - 2026 Year 03 Month 17 Day
Date of IRB - 2026 Year 03 Month 17 Day
Anticipated trial start date - 2026 Year 05 Month 11 Day
Last follow-up date - 2029 Year 09 Month 30 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000070332
Disclaimer: Curated by HT Syndication.