Tokyo, Aug. 29 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062708) titled 'A Prospective Multicenter Study on Episodic Nocturnal Hypercapnia in Chronic Obstructive Pulmonary Disease' on Aug. 27.
Study Type:
Observational
Primary Sponsor:
Institute - Medical Research Institute KITANO HOSPITAL
Condition:
Condition - Chronic Obstructive Pulmonary Disease
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - The objective of this study is to prospectively evaluate whether the presence of episodic nocturnal hypercapnia (eNH), which reflects hypoventilation associated with REM sleep, influences future exacerbation risk and prognosis in patients with stable chronic obstructive pulmonary disease (COPD).
Basic objectives2 - Others
Eligibility:
Age-lower limit - 40
years-old
=40 years
2) Stable chronic obstructive pulmonary disease (COPD)
3) GOLD stage III-IV
4) Clinically stable condition without exacerbation for at least 2 weeks at enrollment
5) Daytime PaCO2 =10 or mMRC grade >=2
Key exclusion criteria - 1) Current use of home oxygen therapy, home high-flow therapy, home NIV, or home CPAP
2) Previous diagnosis or history of obstructive sleep apnea
Target Size - 100
Recruitment Status:
Recruitment status - Preinitiation
Date of protocol fixation - 2026 Year 07 Month 13 Day
Anticipated trial start date - 2026 Year 08 Month 27 Day
Last follow-up date - 2030 Year 09 Month 30 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000070203
Disclaimer: Curated by HT Syndication.
