Tokyo, May 30 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060287) titled 'Prospective study of whether practicing thumb pronation improves pain and hand function in thumb CMC osteoarthritis' on May 30.

Study Type: Interventional

Study Design: Basic Design - Single arm Randomization - Non-randomized Blinding - Open -no one is blinded Control - Self control

Primary Sponsor: Institute - Institute of Science Tokyo

Condition: Condition - Thumb carpometacarpal arthritis Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The aims of this study are to develop a novel exercise therapy for thumb carpometacarpal (CMC) osteoarthritis, to evaluate its usefulness, and ultimately to establish an evidence-based exercise therapy for this condition. In addition, to facilitate simplification, standardization, and wider implementation of the developed exercise therapy, we aim to develop exercise-therapy support devices, including both non-digital and digital options. Because thumb CMC osteoarthritis is a highly prevalent age-related disease, if exercise therapy can improve symptoms and help prevent disease progression, it is expected not only to enhance patients' activities of daily living (ADL) and quality of life (QOL), but also to contribute to reducing healthcare costs, which is an urgent issue in Japan. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - In addition to regular rehabilitation, we provide instruction on thenar muscle training exercises, including opponens pollicis training.

Eligibility: Age-lower limit - 20 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - Thumh CMC osteoarthrits group: Those diagnosed with CM joint arthropathy of the thumb. Those diagnosed with the above disease by an orthopedic specialist based on medical history, physical findings, and imaging tests (plain X-rays). Those aged 20 years or older at the time of consent. Those who have given written consent to participate in this study. Key exclusion criteria - Thumh CMC osteoarthrits group: Those with a history of trauma to the upper limbs or cervical spine. Those with rheumatoid arthritis or other collagen diseases. Those with a history of treatment for malignant tumors or other conditions affecting the upper limbs, shoulder girdle, or neck. Those with neurological paralysis due to cerebrovascular disease or other conditions. Those who have already received treatment at another hospital. Those deemed inappropriate by the principal investigator or co-investigator Target Size - 25

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2026 Year 01 Month 07 Day Anticipated trial start date - 2026 Year 04 Month 30 Day Last follow-up date - 2027 Year 07 Month 30 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068960

Disclaimer: Curated by HT Syndication.