Tokyo, July 21 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000058468) titled 'Efficacy of Dual Antiplatelet Therapy Including P2Y12 Inhibitor Loading in Preventing Motor Function Deterioration in the Acute Phase of Noncardioembolic Ischemic Stroke' on July 20.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Randomized Blinding - Open -no one is blinded Control - Active

Primary Sponsor: Institute - Junshin Hospital Clinical Neurosurgery Research Department

Condition: Condition - Noncardioembolic Ischemic Stroke Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - Motor paralysis represents a significant functional loss in ischemic stroke, leading to impairment in activities of daily living. The objective of this study is to evaluate the preventive effects on motor function deterioration during the acute phase of non-cardioembolic ischemic stroke and to explore the optimal therapeutic approach. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - Patients receiving dual antiplatelet therapy including P2Y12 inhibitor loading Interventions/Control_2 - Patients receiving other antiplatelet therapies

Eligibility: Age-lower limit - 20 years-old = Gender - Male and Female Key inclusion criteria - -Age: 20 to 85 years -Able to start antiplatelet therapy within 48 hours of onset -Diagnosed with non-cardioembolic ischemic stroke Key exclusion criteria - -Cardioembolic stroke -Atherothrombotic cerebral infarction -Stroke of undetermined embolic source -Patients with bleeding diathesis -Patients contraindicated for antiplatelet therapy -Patients for whom motor function assessment is difficult (including higher brain dysfunction and consciousness disturbance) Target Size - 200

Recruitment Status: Recruitment status - Main results already published Date of protocol fixation - 2023 Year 06 Month 30 Day Date of IRB - 2025 Year 07 Month 14 Day Anticipated trial start date - 2023 Year 07 Month 01 Day Last follow-up date - 2025 Year 07 Month 20 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000066852

Disclaimer: Curated by HT Syndication.