Tokyo, March 31 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000059330) titled 'A retrospective clinical study for the contribution of protein-energy wasting, inflammation, and aging in the impact of calcimimetics on survival in dialysis patients' on March 31.
Study Type:
Observational
Primary Sponsor:
Institute - Social medical corporation Kawashimakai Kawashima Hospital
Condition:
Condition - Patients with end-stage kidney disease undergoing hemodialysis and online hemodiafiltration
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - We clarify the involvement of protein-energy wasting, inflammation, and aging on 2-year all-cause mortality by calcimimetics in patients on hemodialysis and online hemodiafiltration with in vitro beta2-microglobulin clearance of 70 mL/min and more.
Basic objectives2 - Safety,Efficacy
Eligibility:
Age-lower limit - 20
years-old
<=
Age-upper limit - Not applicable
Gender - Male and Female
Key inclusion criteria - Patients on maintenance hemodialysis or online hemodialysis as of July 1, 2017
Key exclusion criteria - 1 Use of dialyzers with beta2-microgloburln clearance below 70 mL/min
2 Missing data for covariates at study entry
3 Dialysis conditionssuch as dialysis method, dilution method, and membrane material between April 1, 2017 and June 30, 2017, which are different from those as of July 1, 2017
4 Blood purification methods other than HD
5 Dialysis frequency below 3 sessions per week or dialysis time below 3 hour per session
6 Predilution online hemodiafiltration substitution volume of <60 L and postdilution online hemodiafiltration substitution volume of <8 L
Target Size - 783
Recruitment Status:
Recruitment status - Preinitiation
Date of protocol fixation - 2025 Year 09 Month 03 Day
Anticipated trial start date - 2025 Year 10 Month 10 Day
Last follow-up date - 2026 Year 03 Month 31 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000067867
Disclaimer: Curated by HT Syndication.
