Tokyo, March 31 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000056946) titled 'A retrospective clinical study on the prognosis in dialysis patients between calcimimetic users and non-users' on March 31.

Study Type: Observational

Primary Sponsor: Institute - Social medical corporation Kawashimakai Kawashima Hospital

Condition: Condition - Patients with end-stage kidney disease undergoing hemodialysis and online hemodiafiltration Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - A propensity score matching model and adjusted Cox regression analysis is used in a retrospective 2-year observational study. The effects of 2-year mortality in patients with achievement of P target values and Ca is compared between calcimimetics users and non-users. In addition, chi-square tests is performed to assess the 1-year and 2-year mortality on patients whose P, Ca, and PTH are outside the target range. Basic objectives2 - Safety,Efficacy

Eligibility: Age-lower limit - 20 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - Patients on maintenance hemodialysis or online hemodialysis as of July 1, 2017 Key exclusion criteria - 1 Use of dialyzers with beta2-microgloburln clearance below 70 mL/min 2 Missing data for covariates at study entry 3 Dialysis conditionssuch as dialysis method and membrane material between April 1, 2017 and June 30, 2017, which are different from those as of July 1, 2017 4 Blood purification methods other than hemodialysis and online hemodiafiltration 5 Dialysis frequency below 3 sessions per week or dialysis time below 3 hour per session 6 Pregnant or lactating patients Target Size - 783

Recruitment Status: Recruitment status - Terminated Date of protocol fixation - 2025 Year 01 Month 22 Day Date of IRB - 2025 Year 02 Month 04 Day Anticipated trial start date - 2025 Year 02 Month 06 Day Last follow-up date - 2025 Year 05 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000065038

Disclaimer: Curated by HT Syndication.