Clinical Trial: A retrospective cohort study on predictors of renal function decline in a population at risk for the onset and progression of chronic kidney disease (Japan)

Tokyo, March 10 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060879) titled 'A retrospective cohort study on predictors of renal function decline in a population at risk for the onset and progression of chronic kidney disease' on March 9.

Study Type: Observational

Primary Sponsor: Institute - Division of Nephrology, Hypertension and Endocrinology, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan

Condition: Condition - chronic kidney disease Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The objective of this study is to identify factors associated with renal function decline (progression of chronic kidney disease [CKD]) among patients with CKD and those at high risk for CKD onset (including individuals with diabetes mellitus, hypertension, and obesity), using routinely collected clinical information and laboratory data obtained in daily clinical practice. In addition, this study aims to describe the utilization rates and prescribing patterns of renoprotective agents, such as SGLT2 inhibitors and finerenone, including treatment initiation, continuation, discontinuation, and combination therapy, and to examine the clinical factors associated with these patterns. Basic objectives2 - Others

Eligibility: Age-lower limit - 18 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - Patients who visited the Department of Nephrology, Hypertension, and Endocrinology at Nihon University Itabashi Hospital and were diagnosed with chronic kidney disease, or those with diabetes, hypertension, or obesity who were considered to be at high risk of developing chronic kidney disease in the future, from January 1, 2014 to February 1, 2030. Key exclusion criteria - 1. Persons who express their unwillingness to participate in this study. 2. Persons deemed by the principal investigator to be unsuitable for inclusion in this study for any reason. Target Size - 1500

Recruitment Status: Recruitment status - Open public recruiting Date of protocol fixation - 2026 Year 03 Month 06 Day Date of IRB - 2026 Year 02 Month 24 Day Anticipated trial start date - 2026 Year 03 Month 06 Day Last follow-up date - 2031 Year 02 Month 01 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000069091

Disclaimer: Curated by HT Syndication.