Tokyo, July 26 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000058600) titled 'A retrospective study to evaluate the tolerability of outpatient initiation of platinum-based combination therapy with carboplatin' on July 25.

Study Type: Observational

Primary Sponsor: Institute - Chiba University Hospital

Condition: Condition - Non-small cell lung cancer Classification by malignancy - Malignancy Genomic information - NO

Objective: Narrative objectives1 - Evaluation of the tolerability of outpatient initiation of first-line carboplatin-based combination therapy in patients with advanced or recurrent non-small cell lung cancer. Basic objectives2 - Safety

Eligibility: Age-lower limit - Not applicable Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - Eligible cases are those who meet either (1) or (2) below and also meet (3). (1) Patients with advanced or recurrent non-small cell lung cancer with a performance status (PS) of 0-1 who have started initial systemic chemotherapy with a regimen containing carboplatin. (2) Patients with advanced or recurrent non-small cell lung cancer with a PS of 0-1 who have started initial systemic chemotherapy with a regimen containing carboplatin after molecular targeted drug therapy. (3) Patients who started initial treatment between January 1, 2019 and December 31, 2022. Key exclusion criteria - Patients who meet any of the following criteria will be excluded. Those who have expressed refusal to participate in this study through a disclosure document. Cases in which initial systemic chemotherapy was administered after unplanned emergency hospitalization. Those treated with the Atezolizumab+Bevacizumab+Carboplatin+Paclitaxel (ABCP) regimen (In reality, it takes more than 5-6 hours to administer the drugs, making it difficult to administer the regimen in an outpatient chemotherapy room. Therefore, it is not possible to compare the outpatient and inpatient groups.) Target Size - 400

Recruitment Status: Recruitment status - No longer recruiting Date of protocol fixation - 2024 Year 09 Month 26 Day Date of IRB - 2024 Year 09 Month 26 Day Anticipated trial start date - 2024 Year 09 Month 26 Day Last follow-up date - 2025 Year 03 Month 30 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000067004

Disclaimer: Curated by HT Syndication.