Tokyo, Dec. 15 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060059) titled 'A Comparative Application Study of Human Umbilical Cord-Derived Mesenchymal Stem Cell Conditioned Medium on Skin Dryness and Skin Sensitivity' on Dec. 15.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Randomized Blinding - Single blind -participants are blinded Control - Placebo

Primary Sponsor: Institute - Juntendo University

Condition: Condition - Xerosis and Sensitive Skin Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The purpose of this study is to investigate the effects of the application of human umbilical cord-derived mesenchymal stem cell conditioned medium to the facial skin of healthy volunteers twice daily for three months on skin dryness and skin sensory hypersensitivity (sensitive skin), including pruritus, based on the hypothesis that improvement in skin dryness may alleviate skin sensitivity. Basic objectives2 - Safety,Efficacy

Intervention: Interventions/Control_1 - Application of 0% human umbilical cord-derived mesenchymal stem cell conditioned medium (vehicle only) to the facial skin twice daily after face washing for 3 months. Interventions/Control_2 - Application of 10% human umbilical cord-derived mesenchymal stem cell conditioned medium to the facial skin twice daily after face washing for 3 months.

Eligibility: Age-lower limit - 30 years-old = Gender - Female Key inclusion criteria - 1. Healthy females aged between 30 and 59 years 2. Individuals who have never experienced severe sensitive skin or allergic reactions to cosmetics in the past. 3. Individuals who do not have any chronic inflammatory skin diseases. 4. Individuals who, after receiving a sufficient explanation of the study, have fully understood the contents and have provided written informed consent of their own free will. Key exclusion criteria - 1. Individuals who do not meet the inclusion criteria 2. Individuals whom the principal investigator judges to be inappropriate for participation in this study Target Size - 45

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2025 Year 11 Month 10 Day Date of IRB - 2025 Year 11 Month 19 Day Anticipated trial start date - 2025 Year 12 Month 18 Day Last follow-up date - 2026 Year 09 Month 30 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068685

Disclaimer: Curated by HT Syndication.