Tokyo, Nov. 15 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000063620) titled 'A study on hydrogen inhalation and physiological measurements' on Nov. 15.

Study Type: Interventional

Study Design: Basic Design - Cross-over Randomization - Randomized Blinding - Single blind -participants are blinded Control - Placebo

Primary Sponsor: Institute - NeU Corporation

Condition: Condition - Healthy individuals Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - To investigate the effect of Hydrogen Inhalation on brain activation, heart rate, and cognitive function. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - Participants take cognitive tasks while inhaling hydrogen.After a 30-minute washout period,participants take cognitive tasks while inhaling air. Interventions/Control_2 - Participants take cognitive tasks while inhaling air.After a 30-minute washout period,participants take cognitive tasks while inhaling hydrogen.

Eligibility: Age-lower limit - 25 years-old = Gender - Male and Female Key inclusion criteria - Living in Tokyo,Kanagawa,Chiba or Saitama. Male and female adults (25-45 years old) Native Japanese speakers Right-handed No health problem for now (No history of serious illness / mental disorder) Having normal or corrected-to-normal vision for both eyes (greater than or equal to 0.7) Having no family members working in newspaper publishing or broadcasting, mass media or advertising, market research or consulting, or the electrical appliance industry. Key exclusion criteria - Smoker (including e-cigarettes) Taking any medication on a daily basis Pregnant or breastfeeding Having respiratory diseases (such as asthma or chronic obstructive pulmonary disease) Having difficulty using a nasal cannula due to nasal congestion or nasal disease When the investigator in charge judges that participating in this experiment is not appropriate. Target Size - 24

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2026 Year 11 Month 13 Day Date of IRB - 2026 Year 11 Month 12 Day Anticipated trial start date - 2026 Year 11 Month 16 Day Last follow-up date - 2027 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000072810

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