Tokyo, Nov. 18 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000059799) titled 'Shock Index-Guided Selection of Embolic Material for Emergency Uterine Artery Embolization in Postpartum Hemorrhage' on Nov. 17.
Study Type:
Observational
Primary Sponsor:
Institute - Tokyo Medical University
Condition:
Condition - Obstetric hemorrhage
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - Uterine artery embolization (UAE) is an effective hemostatic intervention for managing obstetric hemorrhage. Temporary embolic agents are generally preferred to preserve fertility; however, achieving hemostasis can be challenging in patients with disseminated intravascular coagulation (DIC). This study aimed to determine the optimal selection of embolic agents based on the shock index (SI), a simple indicator of bleeding severity, to help minimize bleeding.
Basic objectives2 - Efficacy
Eligibility:
Age-lower limit - 18
years-old
<=
Age-upper limit - Not applicable
Gender - Female
Key inclusion criteria - Patients requiring uterine artery embolisation at our hospital due to uncontrollable haemorrhage from the following conditions:
1. Postpartum haemorrhage
2. Placenta praevia, placenta accreta haemorrhage
3. Haemorrhage due to retained placenta accreta
4. Uterine inversion
5. Perineal laceration
6. Post-hysterectomy haemorrhage
Key exclusion criteria - Patients under 18 years of age at the time of implementation in the UAE
Patients who declined to participate in the study
Target Size - 48
Recruitment Status:
Recruitment status - Preinitiation
Date of protocol fixation - 2025 Year 02 Month 12 Day
Anticipated trial start date - 2025 Year 11 Month 18 Day
Last follow-up date - 2027 Year 03 Month 31 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068374
Disclaimer: Curated by HT Syndication.
