Tokyo, Sept. 1 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061354) titled 'A Study on the Secretory Dynamics of GLP-1 Following Beverage Consumption' on Sept. 1.

Study Type: Interventional

Study Design: Basic Design - Cross-over Randomization - Non-randomized Blinding - Open -no one is blinded Control - Placebo

Primary Sponsor: Institute - Kyoto Prefectural University of Medicine

Condition: Condition - Volunteer Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - To clarify changes in blood GLP-1 concentration following consumption of functional beverages (matcha beverage, flavonoid-containing beverage, whey protein beverage, green tea catechin beverage, indigestible dextrin-containing beverage). Basic objectives2 - Others

Intervention: Interventions/Control_1 - This study evaluates GLP-1 secretion dynamics after consuming five types of functional beverages in healthy adults. Each subject will consume the five beverages on separate days, with changes in hormone dynamics (including GLP-1) and blood glucose levels observed before and after consumption. No randomization will be performed; all subjects will consume the five beverages in the same order (Visit 1: Beverage A, Visit 2: Beverage B, Visit 3: Beverage C, Visit 4: Beverage D, Visit 5: Beverage E). Interventions/Control_2 - This study evaluates GLP-1 secretion dynamics after consuming five types of functional beverages in healthy adults. Each subject will consume the five beverages on separate days, with changes in hormone dynamics (including GLP-1) and blood glucose levels observed before and after consumption. No randomization will be performed; all subjects will consume the five beverages in the same order (Visit 1: Beverage A, Visit 2: Beverage B, Visit 3: Beverage C, Visit 4: Beverage D, Visit 5: Beverage E).

Eligibility: Age-lower limit - 18 years-old = Gender - Male and Female Key inclusion criteria - 1. Individuals capable of providing written informed consent to participate in the study of their own free will 2. Age: 18 years or older and 65 years or younger 3. Individuals capable of understanding the content of this study and adhering to the trial schedule Key exclusion criteria - 1. Individuals with severe heart disease, liver disease, kidney disease, or endocrine disorders 2. Individuals with a history of or currently undergoing treatment for gastrointestinal disorders (e.g., inflammatory bowel disease, irritable bowel syndrome) 3. Individuals allergic to dairy products, soy, or tea 4. Women who are pregnant, may be pregnant, or are breastfeeding 5. Individuals with a history of anemia or currently undergoing treatment for anemia 6. Individuals with sensitivity to caffeine 7. Individuals deemed unsuitable by their primary physician or the principal investigator Target Size - 20

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2026 Year 04 Month 22 Day Anticipated trial start date - 2026 Year 06 Month 01 Day Last follow-up date - 2027 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000069496

Disclaimer: Curated by HT Syndication.