Tokyo, Nov. 5 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000059633) titled 'A systematic review of the functional role of bilberry-derived anthocyanins in alleviating eye fatigue' on Nov. 4.

Study Type: Others,meta-analysis etc

Primary Sponsor: Institute - FANCL Corporation

Condition: Condition - Healthy adults Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The aim of this study is to evaluate the functional role of bilberry-derived anthocyanins in alleviating eye fatigue. Basic objectives2 - Efficacy

Eligibility: Age-lower limit - 18 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - P: Participant The subjects were healthy adults (those who are not suffering from any diseases, excluding those under 18 years old, pregnant women, and lactating women).

I: Intervention(food) characteristics The intake of ingredients was equivalent to the anthocyanins derived from bilberry used in the final product. There were no restrictions on intake amount, intake period, or follow-up period.

C: Comparison group Comparisons were made with a placebo group or a control group in which the test food was replaced with a food that did not contain bilberry-derived anthocyanins.

O: Evaluation items Main outcomes: Relieves eye fatigue by improving the eye's accommodative function (near point distance, accommodative power, and accommodative time). Secondary outcomes: Effect in relieving eye fatigue based on subjective evaluations (VAS, subjective symptom questionnaires, etc.).

S: Research design The research designs used in the included literature were randomized parallel-group controlled trials (RCTPs), randomized crossover trials (RCTCOs), and quasi-randomized controlled trials (quasi-RCTs).The included studies were written in Japanese or English. In principle, the presentation format was an original paper; however, short reports or summaries were also accepted if the content was clearly specified.Abstracts from academic conference presentations (conference proceedings) were excluded due to insufficient descriptive content. Whether or not the journal was peer-reviewed was not used as an exclusion criterion.To minimize publication bias, studies with results published in clinical trial registry databases were also included.Regarding gray literature, doctoral theses and reports from government agencies or think tanks were included if their detailed content could be identified. Key exclusion criteria - The literature which does not meet the key inclusion criteria will be excluded.

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2025 Year 10 Month 08 Day Anticipated trial start date - 2025 Year 11 Month 04 Day Last follow-up date - 2025 Year 12 Month 22 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068208

Disclaimer: Curated by HT Syndication.