Tokyo, March 31 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000057951) titled 'A verification study of blood amino acid levels at intake of protein material' on March 31.
Study Type:
Interventional
Study Design:
Basic Design - Cross-over
Randomization - Randomized
Blinding - Double blind -all involved are blinded
Control - Active
Primary Sponsor:
Institute - Mitsubishi Corporation Life Sciences Limited
Condition:
Condition - Healthy Japanese
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - To verify blood amino acid levels at intake of protein material and the absorption of protein material. To characterize protein derived from test material A by verifying protein utilization and absorption rate compared to existing milk protein (animal) and soy protein (plant).
Basic objectives2 - Efficacy
Intervention:
Interventions/Control_1 - Duration: Single ingestion (three times)
Test product:
Protein derived from test material A
Soy protein
Milk protein (whey protein)
Intake method:
Add 200 mL of water and the test product to a shaker container, intake after thoroughly stirring. Immediately afterward, add 100 mL of water again to the empty shaker container and intake after thoroughly stirring for total consumption. Then intake 50 mL of water for oral refreshment. (The entire process described above should be conducted over a period of five minutes so that all individuals are at the same pace.)
*The washout period is at least one week.
*The intervention sequence is Test 1 to Test 3.
Interventions/Control_2 - Duration: Single ingestion (three times)
Test product:
Soy protein
Milk protein (whey protein)
Protein derived from test material A
Intake method:
Add 200 mL of water and the test product to a shaker container, intake after thoroughly stirring. Immediately afterward, add 100 mL of water again to the empty shaker container and intake after thoroughly stirring for total consumption. Then intake 50 mL of water for oral refreshment. (The entire process described above should be conducted over a period of five minutes so that all individuals are at the same pace.)
*The washout period is at least one week.
*The intervention sequence is Test 1 to Test 3.
Eligibility:
Age-lower limit - 20
years-old
Gender - Male and Female
Key inclusion criteria - 1. Japanese
2. Men or women
3. Individuals aged >= 20 and = 18.5 kg/m2 and = 60 g/day a week
8. Individuals who are smokers or have quit smoking within the last year
9. Individuals whose lifestyles or dietary habits are irregular due to working a late-night shift or others
10. Individuals who have food allergies or food intolerances including the test foods and the prescribed food
11. Individuals who have a history of serious diseases of digestive organs, or surgical history of digestive organs
12. Individuals who have developed abdominal pain or gastrointestinal symptoms due to consuming high-protein foods
13. Individuals who have or have a history of a diseases which influence digestion and absorption of nutrients
14. Individuals who are taking steroids, protease inhibitors, or antipsychotics
15. Individuals who are pregnant, lactating, or planning to become pregnant during this study
16. Individuals who have been enrolled in other clinical studies within the last 28 days before the agreement to participate in this study or plan to participate in another study during this study
17. Individuals who are judged as ineligible to participate in this study by the physician
Target Size - 15
Recruitment Status:
Recruitment status - Completed
Date of protocol fixation - 2025 Year 05 Month 12 Day
Date of IRB - 2025 Year 05 Month 12 Day
Anticipated trial start date - 2025 Year 05 Month 23 Day
Last follow-up date - 2025 Year 08 Month 04 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000066251
Disclaimer: Curated by HT Syndication.