Tokyo, Aug. 5 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062467) titled 'A verification study of the effects of test food consumption on postprandial blood glucose levels in healthy Japanese' on Aug. 4.
Study Type:
Interventional
Study Design:
Basic Design - Cross-over
Randomization - Randomized
Blinding - Double blind -all involved are blinded
Control - Placebo
Primary Sponsor:
Institute - Tsuno Rice Fine Chemicals Co., Ltd
Condition:
Condition - Healthy Japanese
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - To verify the effects of test food consumption on postprandial blood glucose levels in healthy Japanese
Basic objectives2 - Efficacy
Intervention:
Interventions/Control_1 -
Single ingestion
Test 1: Food containing rice bran extract
Test 2: Food not containing rice bran extract
Load food: Bread (Pasco Shikishima Corporation), strawberry jam (Sudo Jam Co., Ltd.)
Test 1: Consume 10 capsules with water 30 minutes before the load food consumption.
Test 2: Consume 10 capsules with water 30 minutes before the load food consumption.
Load food: At screening, after the completion of the pre-consumption test, and at the main test, 30 minutes after the test product consumption, consume 1 slice of bread (4-sliced) and 20 g of strawberry jam over 5 minutes.
*The daily dose should be consumed within the same day and should not be carried over to the following day.
* Test 1 followed by Test 2.
* The washout period is 1 week or more.
Interventions/Control_2 -
Single ingestion
Test 1: Food not containing rice bran extract
Test 2: Food containing rice bran extract
Load food: Bread (Pasco Shikishima Corporation), strawberry jam (Sudo Jam Co., Ltd.)
Test 1: Consume 10 capsules with water 30 minutes before the load food consumption.
Test 2: Consume 10 capsules with water 30 minutes before the load food consumption.
Load food: At screening, after the completion of the pre-consumption test, and at the main test, 30 minutes after the test product consumption, consume 1 slice of bread (4-sliced) and 20 g of strawberry jam over 5 minutes.
*The daily dose should be consumed within the same day and should not be carried over to the following day.
* Test 1 followed by Test 2.
* The washout period is 1 week or more.
Eligibility:
Age-lower limit - 18
years-old
<=
Age-upper limit - Not applicable
Gender - Male and Female
Key inclusion criteria - 1. Japanese
2. Men or women
3. Adults
4. Healthy individuals
5. Individuals whose blood glucose level is relatively high
6. Individuals whose IAUC of GLU is relatively large at screening
7. Individuals whose BMI is relatively high
Key exclusion criteria - 1. Individuals who are receiving treatment for or have a history of malignant tumors, heart failure, or myocardial infarction
2. Individuals who have an implanted pacemaker or implantable cardioverter defibrillator
3. Individuals who are currently undergoing treatment for any of the following chronic diseases: cardiac arrhythmia, liver disorder, chronic kidney disease, cerebrovascular disorder, rheumatic disease, diabetes mellitus, dyslipidemia, hypertension, or any other chronic diseases
4. Individuals who consume Foods for Specified Health Uses or Foods with Functional Claims
5. Individuals who are taking or using medications (including herbal medicines) or supplements
6. Individuals who are allergic to medications or foods related to the test product (particularly, rice, wheat, milk ingredients, or pork)
7. Individuals who are smokers or have not yet completed one year since quitting smoking
8. Individuals who are pregnant, lactating, or planning pregnancy during this study
9. Individuals who are deemed unsuitable for participation in this study by the principal investigator
Target Size - 10
Recruitment Status:
Recruitment status - Open public recruiting
Date of protocol fixation - 2026 Year 07 Month 21 Day
Date of IRB - 2026 Year 07 Month 21 Day
Anticipated trial start date - 2026 Year 08 Month 04 Day
Last follow-up date - 2026 Year 09 Month 25 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000071497
Disclaimer: Curated by HT Syndication.