Tokyo, July 2 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062109) titled 'An initiative for frailty prevention by improving intestinal environment in community-dwelling elderly' on July 1.

Study Type: Interventional

Study Design: Basic Design - Single arm Randomization - Non-randomized Blinding - Open -no one is blinded Control - Uncontrolled

Primary Sponsor: Institute - Nagoya University of Arts and Sciences

Condition: Condition - Healthy elderly Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - To evaluate the effects of 8-week intake of a prebiotic sweetener (containing inulin, kestose, and agaro-oligosaccharide) on dietary habits, gut microbiota (diversity, abundance of beneficial bacteria), and frailty-related factors (physical function, cognitive function, and nutritional status) in healthy elderly individuals residing in N City. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - Daily intake of prebiotic sweetener (syrup containing inulin, kestose, and agaro-oligosaccharide) using a dedicated spoon (approx. 17g/day: containing 3.4g kestose, 8.5g inulin, and 17mg agaro-oligosaccharide) at breakfast for 8 weeks.

Eligibility: Age-lower limit - 65 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - Healthy residents of N City aged 65 or older will be recruited through the city's public relations newsletter. Eligible participants include both men and women who have no physician-diagnosed gastrointestinal diseases and have provided written informed consent. Key exclusion criteria - - Target Size - 50

Recruitment Status: Recruitment status - Completed Date of protocol fixation - 2024 Year 08 Month 19 Day Date of IRB - 2024 Year 09 Month 23 Day Anticipated trial start date - 2024 Year 10 Month 22 Day Last follow-up date - 2026 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000071067

Disclaimer: Curated by HT Syndication.