Tokyo, Sept. 30 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062932) titled 'Analysis of the molecular pathology of the vasculitis syndromes using clinical biopsies' on Sept. 30.

Study Type: Observational

Primary Sponsor: Institute - Tokyo Metropolitan Institute of Medical Science (TMiMS)

Condition: Condition - vasculitis designated intractable disease (Giant cell arteritis, Takayasu arteritis, polyarteritis nodosa etc.) Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - This study aims to elucidate disease specific pathophysiological mechanisms in vasculitis syndromes by obtaining molecular data from blood and tissue samples collected for definitive diagnosis. Furthermore, the study seeks to identify factors correlating with disease activity and treatment response in each condition and to evaluate their utility in diagnostic and therapeutic strategies. Basic objectives2 - Others

Eligibility: Age-lower limit - 20 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - Patients suspected of having refractory vasculitis who are undergoing diagnosis (e.g., via histopathology) or treatment, and who meet the following criteria: (1) Patients who provide consent to participate in this study (2) Patients aged 20 years or older (3) Patients who are receiving outpatient care or are hospitalized at a participating medical institution Key exclusion criteria - (1) Patients who do not provide consent for this study or who withdraw their consent (2) Patients whom the attending physician deems unsuitable for participation in this study Target Size - 100

Recruitment Status: Recruitment status - No longer recruiting Date of protocol fixation - 2026 Year 09 Month 30 Day Date of IRB - 2019 Year 04 Month 25 Day Anticipated trial start date - 2026 Year 09 Month 30 Day Last follow-up date - 2029 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000072055

Disclaimer: Curated by HT Syndication.