Tokyo, June 27 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062071) titled 'Assessment of Hemodynamic Changes Before and After Lower Limb Tourniquet Release During Orthopedic Surgery Using Carotid Artery Blood Flow: A Prospective Observational Study' on June 26.
Study Type:
Observational
Primary Sponsor:
Institute - JA Onomichi general hospital
Condition:
Condition - Patients undergoing lower limb orthopedic surgery under general anesthesia
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - The objective of this study is to quantitatively evaluate changes in systemic hemodynamics associated with hypotension following lower limb tourniquet release.
Basic objectives2 - Others
Eligibility:
Age-lower limit - 15
years-old
=
Gender - Male and Female
Key inclusion criteria - Patients undergoing lower limb orthopedic surgery under general anesthesia
ASA-PS 1-3
Key exclusion criteria - Known carotid artery disease (e.g., severe carotid artery stenosis or a history of carotid artery surgery)
Severe cardiac arrhythmias (e.g., atrial fibrillation)
Severe structural heart disease (e.g., aortic stenosis or moderate-to-severe valvular regurgitation)
Patients in whom adequate carotid pulse-wave Doppler ultrasound images cannot be obtained because of anatomical limitations
Target Size - 30
Recruitment Status:
Recruitment status - Open public recruiting
Date of protocol fixation - 2026 Year 06 Month 22 Day
Date of IRB - 2026 Year 06 Month 25 Day
Anticipated trial start date - 2026 Year 06 Month 25 Day
Last follow-up date - 2029 Year 12 Month 31 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000071024
Disclaimer: Curated by HT Syndication.
