Tokyo, Dec. 23 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060157) titled 'Association between Acute Exercise-Induced Brain Region-Specific Endocannabinoid Expression and Anxiety-Like Behavior in Mice' on Dec. 22.
Study Type:
Interventional
Study Design:
Basic Design - Parallel
Randomization - Randomized
Blinding - Open -no one is blinded
Control - No treatment
Primary Sponsor:
Institute - Yamanashi Gakuin University
Condition:
Condition - Healthy male mice
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - We will infer the molecular mechanisms underlying changes in the human brain, which are difficult to observe directly, based on findings from animal models.
Basic objectives2 - Efficacy
Intervention:
Interventions/Control_1 - non-stress+rest, the stress condition consisted of restraint in a 50-mL conical tube for 2 hours, while the exercise condition involved treadmill running at 10 m/min.
Interventions/Control_2 - non-stress+exercise, the stress condition consisted of restraint in a 50-mL conical tube for 2 hours, while the exercise condition involved treadmill running at 10 m/min.
Eligibility:
Age-lower limit - 6
weeks-old
=
Gender - Male
Key inclusion criteria - Healthy male C57BL/6J mice, aged 8 weeks, experimentally naive, and acclimatized to laboratory conditions.
Key exclusion criteria - Mice were excluded from the analysis if they showed visible signs of injury or refused to run on the treadmill despite encouragement.
Target Size - 32
Recruitment Status:
Recruitment status - No longer recruiting
Date of protocol fixation - 2025 Year 06 Month 01 Day
Date of IRB - 2025 Year 06 Month 30 Day
Anticipated trial start date - 2025 Year 07 Month 15 Day
Last follow-up date - 2026 Year 03 Month 31 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068804
Disclaimer: Curated by HT Syndication.
