Tokyo, May 28 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061710) titled 'Hematological Inflammatory Indices and Coronary Microvascular Endotypes in Patients with Angina and Non-Obstructive Coronary Arteries' on May 27.
Study Type:
Observational
Primary Sponsor:
Institute - Tsuchiura Kyodo General Hospital
Condition:
Condition - Angina with Non-Obstructive Coronary Arteries
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - The aim of this study is to investigate the association between hematological inflammatory indices and ANOCA phenotypes, including coronary microvascular dysfunction and coronary vasospasm, in patients with angina and non-obstructive coronary arteries. In particular, this study will examine whether monocyte-dominant inflammatory markers, such as the monocyte-to-lymphocyte ratio and monocyte-to-hematocrit ratio, are associated with structural coronary microvascular dysfunction defined by coronary flow reserve and the index of microcirculatory resistance.
Basic objectives2 - Efficacy
Eligibility:
Age-lower limit - 20
years-old
0.80, are included.
Key exclusion criteria - Patients with acute coronary syndrome, those undergoing hemodialysis, those with incomplete physiological or laboratory data, and those with poor pressure waveform quality are excluded.
Target Size - 200
Recruitment Status:
Recruitment status - Completed
Date of protocol fixation - 2026 Year 04 Month 19 Day
Date of IRB - 2026 Year 04 Month 24 Day
Anticipated trial start date - 2026 Year 04 Month 24 Day
Last follow-up date - 2026 Year 05 Month 27 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000070583
Disclaimer: Curated by HT Syndication.
