Tokyo, Jan. 25 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060448) titled 'Biomechanical Components of Pinch in Patients with Thumb Carpometacarpal Osteoarthritis and After Thumb Opposition Reconstruction' on Jan. 23.

Study Type: Interventional

Study Design: Basic Design - Single arm Randomization - Non-randomized Blinding - Open -no one is blinded Control - Self control

Primary Sponsor: Institute - Niigata University of Health and Welfare

Condition: Condition - Thumb Carpometacarpal Osteoarthritis and Patients with Carpal Tunnel Syndrome Following Thumb Opposition Reconstruction Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The objective of this study is to quantitatively analyze biomechanical components (forces and torques) and muscle activity during pinching tasks in patients with thumb carpometacarpal osteoarthritis and in patients following thumb opposition reconstruction for carpal tunnel syndrome, using a pinch meter and surface electromyography, and to clarify differences in functional characteristics associated with disease and postoperative conditions. Basic objectives2 - Others

Intervention: Interventions/Control_1 - The intervention in this study consists of performing standardized pinching tasks designed for research purposes. Participants perform the pinching tasks in a seated position under predefined force conditions according to instructions. These tasks are conducted once for measurement and assessment only and are not intended as therapeutic interventions.

Eligibility: Age-lower limit - 20 years-old = Gender - Male and Female Key inclusion criteria - Participants who meet one of the following criteria and provide written informed consent:

Individuals diagnosed with thumb carpometacarpal osteoarthritis by a physician.

Individuals who have undergone thumb opposition reconstruction for carpal tunnel syndrome and are in a stable postoperative condition.

Healthy individuals without apparent upper limb functional impairment. Key exclusion criteria - Participants meeting any of the following criteria will be excluded:

Individuals with severe pain, inflammation, or acute injury of the upper limb that interferes with performing pinching tasks.

Individuals with upper limb disorders other than thumb carpometacarpal osteoarthritis (e.g., rheumatoid arthritis, severe osteoarthritis, peripheral neuropathy).

Individuals with a history of stroke, neuromuscular disease, or central nervous system disorders.

Individuals deemed inappropriate for participation by the investigators. Target Size - 30

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2026 Year 01 Month 23 Day Anticipated trial start date - 2026 Year 01 Month 23 Day Last follow-up date - 2028 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000069156

Disclaimer: Curated by HT Syndication.