Tokyo, Feb. 1 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000059452) titled 'Can implant prostheses improve cognitive function in older adults?' on Feb. 1.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Non-randomized Blinding - Open -no one is blinded Control - Active

Primary Sponsor: Institute - Institute of Science Tokyo

Condition: Condition - parcial/complete edentulouness Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - To investigate whether there is a difference in the effects on cognitive function between wearing implant prostheses and wearing removable dentures. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - To fabricate and set a fixed implant prosthesis or a removable implant prosthesis (IOD, implant-supported removable partial denture (IARPD)) for the missing teeth area, performing adjustments as needed. Interventions/Control_2 - To fabricate and set a complete denture or a partial denture for the missing teeth area, performing adjustments as needed

Eligibility: Age-lower limit - 65 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - Aged 65 or older Individuals who have lost occlusal support Individuals who plan to restore the edentulous area with fixed implant prostheses, removable implant prostheses, or removable dentures, or for whom such restoration has been decided Key exclusion criteria - Individuals with poorly controlled systemic diseases History of BP medication use History of chemotherapy or radiation therapy to the head and neck Heavy smokers (10 or more cigarettes per day) Infectious diseases Mental disorders Temporomandibular joint disorders Other individuals deemed ineligible by the principal investigator or co-investigators Target Size - 44

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2025 Year 02 Month 01 Day Anticipated trial start date - 2025 Year 03 Month 01 Day Last follow-up date - 2029 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000067994

Disclaimer: Curated by HT Syndication.