Tokyo, Dec. 1 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000059927) titled 'Changes in Cerebral Blood Flow During Swallowing and Dual-Task Conditions Using Near-Infrared Spectroscopy: A Study in Healthy Subjects' on Nov. 30.

Study Type: Observational

Primary Sponsor: Institute - Tokyo Women's Medical University

Condition: Condition - Healthy subjects Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - This study employs functional near-infrared spectroscopy (fNIRS) to identify the higher-level cortical regions driving the masticatory center during swallowing. Furthermore, it analyzes cortical responses during dual-task training involving simultaneous motor and cognitive tasks. The objective is to demonstrate the efficacy of dual-task training in enhancing swallowing function using clinical indicators and cerebral blood flow dynamics assessment, thereby establishing an effective approach for dysphagia in dementia patients. As a preliminary experiment, we will use functional near-infrared spectroscopy (fNIRS) in healthy subjects to identify brain regions involved in performing dual tasks.

Translated with DeepL.com (free version) Basic objectives2 - Efficacy

Eligibility: Age-lower limit - 20 years-old = Gender - Male and Female Key inclusion criteria - Adults aged 20 to 65 years Individuals without serious chronic diseases (diabetes, hypertension, heart disease, kidney disease, etc.) Individuals in good oral and general health (as determined by the principal investigator or self-report) Individuals who understand the purpose and procedures of the study and have provided written consent Key exclusion criteria - Individuals with a history of neurological disorders, psychiatric disorders, or severe systemic diseases Individuals who have undergone major surgery within the past 6 months Individuals for whom significant changes in health status are anticipated during the study period Other individuals deemed unsuitable by the principal investigator Target Size - 20

Recruitment Status: Recruitment status - Open public recruiting Date of protocol fixation - 2025 Year 06 Month 16 Day Date of IRB - 2026 Year 06 Month 16 Day Anticipated trial start date - 2025 Year 06 Month 17 Day Last follow-up date - 2026 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068539

Disclaimer: Curated by HT Syndication.