Tokyo, Nov. 5 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000059637) titled 'Radiological and histological analysis of alveolar ridge preservation using octacalcium phosphate collagen composite(OCP/Col)' on Nov. 5.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Non-randomized Blinding - Open -no one is blinded Control - Active

Primary Sponsor: Institute - Tohoku University

Condition: Condition - missing tooth Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The purpose of this study is to evaluate the bone regeneration capability of Octacalcium Phosphate Collagen Composites (OCP/Col) when used alone for ridge preservation procedures (ARP), from radiographic and histological perspectives. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - In patients scheduled for ridge preservation (ARP) at the time of extraction with implant therapy planned, the molar group(OCP-M group) using Octacalcium Phosphate Collagen (OCP/Col) was designated (OCP-M group). Interventions/Control_2 - In patients scheduled for ridge preservation (ARP) at the time of extraction with implant therapy planned, the anterior teeth and premolar group (OCP-IP group) using Octacalcium Phosphate Collagen (OCP/Col) was designated.

Eligibility: Age-lower limit - 18 years-old 7) Patients currently using or with a history of bisphosphonate preparations or denosumab Patients with neurocognitive disorders Smokers Patients on steroids Patients using immunosuppressants Patients with liver dysfunction or kidney dysfunction Patients undergoing chemotherapy or radiotherapy, or with a history of head and neck radiotherapy Pregnant or breastfeeding women Patients who did not wish to participate in this study Patients who withdrew consent to participate Patients in whom histological examination could not be performed due to anatomical requirements, etc. Patients with alveolar bone damage caused by tooth extraction procedures Patients in whom the specimen for bone biopsy was damaged or its orientation was unclear, making analysis impossible Target Size - 48

Recruitment Status: Recruitment status - No longer recruiting Date of protocol fixation - 2023 Year 07 Month 26 Day Date of IRB - 2023 Year 07 Month 26 Day Anticipated trial start date - 2023 Year 07 Month 26 Day Last follow-up date - 2026 Year 06 Month 30 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068214

Disclaimer: Curated by HT Syndication.