Tokyo, Dec. 25 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060197) titled 'Comparative Effects of 12-Week Resistance Training on Muscle Stiffness, Co-activation, and Balance in Older Adults with Knee Osteoarthritis' on Dec. 24.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Randomized Blinding - Open -but assessor(s) are blinded Control - Active

Primary Sponsor: Institute - Qufu Normal University

Condition: Condition - Knee Osteoarthritis Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - To compare the effects of a 12-week resistance training program on unstable versus stable surfaces on muscle stiffness, muscle co-activation, and balance in older adults with knee osteoarthritis. The objective is to determine which training condition is more effective in improving musculoskeletal function and postural control. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - Participants in the URT group will undergo a 12 week resistance training program performed on unstable surfaces (e.g., BOSU balls or balance pads). Training will be conducted 3 times per week, each session lasting approximately 45 to 60 minutes, and includes exercises like squats, lunges, and leg extensions. Exercise intensity will progressively increase over. time. Sessions will be supervised by trained physiotherapists. Interventions/Control_2 - Participants in the SRT group will undergo the same 12-week resistance training protocol as the URT group, but on stable surfaces (e.g., gym floor or exercise mats). The frequency, duration, and exercise types are identical, but without surface instability. Sessions will also be supervised by trained physiotherapists.

Eligibility: Age-lower limit - 65 months-old = Gender - Male and Female Key inclusion criteria - Aged 60 years or older

Clinically diagnosed with knee osteoarthritis according to ACR criteria

Able to walk independently without assistive devices

Willing and able to participate in a 12-week resistance training program

Provided written informed consent Key exclusion criteria - Presence of neurological disorders affecting motor function.

Severe cardiovascular or respiratory disease that contraindicates exercise.

Recent knee surgery or intra-articular injection within the past 6 months.

Participation in other structured exercise programs during the study period.

Cognitive impairment that affects ability to follow instructions. Target Size - 50

Recruitment Status: Recruitment status - Completed Date of protocol fixation - 2024 Year 04 Month 01 Day Date of IRB - 2024 Year 04 Month 01 Day Anticipated trial start date - 2024 Year 06 Month 01 Day Last follow-up date - 2025 Year 10 Month 01 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068852

Disclaimer: Curated by HT Syndication.