Tokyo, Jan. 14 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060337) titled 'Efficacy study of the skincare product' on Jan. 13.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Randomized Blinding - Single blind -participants are blinded Control - Active

Primary Sponsor: Institute - DRC Co., Ltd.

Condition: Condition - Not applicable Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - Comparing the efficacy of skincare products between SSL-RNA clusters. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - The test product (1) (a commercially available skincare cosmetic) will be applied to the entire face twice daily for four weeks. Interventions/Control_2 - The test product (2) (a commercially available skincare cosmetic) will be applied to the entire face twice daily for four weeks.

Eligibility: Age-lower limit - 35 years-old = Gender - Female Key inclusion criteria - 1.Female participants aged 35 to 59 years. 2.Individuals who have previously experienced discomfort or adverse skin reactions to skincare cosmetics (*) and consequently discontinued their use. *Examples include skin redness, stinging or tingling sensations, or acne formation. 3.Individuals who are concerned about wrinkles around the outer corners of the eyes (crow's feet). 4. Individuals who are not currently using any facial serum (beauty essence). Key exclusion criteria - 1.Individuals who have skin conditions such as atopic dermatitis or other dermatological symptoms on the test area (face). 2.Individuals who are pregnant or may be pregnant at the time of obtaining nformed consent. 3.Individuals who are breastfeeding or plan to breastfeed during the study period. 4.Individuals who are currently visiting a medical institution due to poor hysical condition or skin disease at the time of recruitment. 5.Individuals who have severe allergies (e.g., hay fever or rhinitis) that may affect the study results. 6.Individuals who regularly take prescription or over-the-counter medications including antibiotics, anti-inflammatory drugs, anti-allergy drugs, sleeping pills, analgesics, hormonal agents, laxatives, or intestinal regulators). Occasional use, about once or twice a month, is acceptable. 7.Individuals who have received cosmetic medical treatments such as peeling or laser therapy on the face or body within the past six months. 8.Individuals who themselves, or whose family members living in the same household, are employed in advertising agencies, market research or consulting firms, mass media, distribution, or in the manufacture of pharmaceuticals, cosmetics, toiletries, or hygiene products. 9.Individuals who are currently participating, or plan to participate during this study, in another interventional study (e.g., involving cosmetics or foods) targeting the facial skin. 10.Individuals who are deemed unsuitable for study participation by the principal investigator for any other reason. Target Size - 120

Recruitment Status: Recruitment status - No longer recruiting Date of protocol fixation - 2025 Year 09 Month 17 Day Date of IRB - 2025 Year 09 Month 17 Day Anticipated trial start date - 2025 Year 10 Month 28 Day Last follow-up date - 2025 Year 11 Month 18 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000069021

Disclaimer: Curated by HT Syndication.