Tokyo, Jan. 25 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060450) titled 'Comparison of Physiological Responses to Constant Load Exercise at Ventilatory Threshold Intensity and High-Intensity Interval Exercise During Wheelchair Propulsion' on Jan. 23.

Study Type: Interventional

Study Design: Basic Design - Cross-over Randomization - Randomized Blinding - Open -no one is blinded Control - Dose comparison

Primary Sponsor: Institute - Fukushima Medical University

Condition: Condition - Healthy participants Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The aim of this study is to clarify the physiological characteristics associated with different exercise modalities during wheelchair propulsion. To achieve this, we compared steady-state exercise and high-intensity interval exercise by comprehensively analyzing the time-series changes in upper and lower limb muscle oxygenation, PFC cerebral oxygenation, cardiac output, respiratory metabolism, and muscle activity. Basic objectives2 - Bio-equivalence

Intervention: Interventions/Control_1 - Cardiopulmonary exercise testing Interventions/Control_2 - Wheelchair propulsion exercise

Eligibility: Age-lower limit - 18 years-old = Gender - Male Key inclusion criteria - 1. Healthy males aged 18 years or older 2. No history of orthopedic disorders in the upper or lower limbs that would interfere with exercise 3. No history of cardiopulmonary or neurological diseases 4. Individuals who provided written informed consent after receiving a full explanation of the study's purpose and procedures Key exclusion criteria - 1. History of cardiovascular disease (e.g., arrhythmia, heart failure, severe hypertension) 2. History of respiratory disease (e.g., asthma, chronic respiratory failure) 3. Acute or chronic orthopedic pain or disorders that limit exercise performance 4. Difficulty attaching electrodes or sensors due to dermatological conditions or skin allergies 5. Initiation of a new high-intensity exercise training regimen during the study period 6. Individuals deemed by the investigator to be unable to participate safely 7. Principal investigator or co-investigators of the present study Target Size - 16

Recruitment Status: Recruitment status - Enrolling by invitation Date of protocol fixation - 2026 Year 01 Month 21 Day Date of IRB - 2026 Year 01 Month 21 Day Anticipated trial start date - 2026 Year 01 Month 23 Day Last follow-up date - 2027 Year 04 Month 30 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000069159

Disclaimer: Curated by HT Syndication.