Tokyo, Oct. 16 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000059412) titled 'Computational approaches to address spatial neglect' on Oct. 15.

Study Type: Observational

Primary Sponsor: Institute - Waseda University

Condition: Condition - Healthy Stroke Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - Conventional treatments for unilateral spatial neglect focus on attention, directing training, but such methods are limited when attention networks are damaged, making outcomes dependent on patients' abilities. This study explores a method to promote responses to the neglected space without engaging the attentional network. Express visuomotor response (EVR; a rapid limb adjustment to sudden target shifts during reaching) occurs through a reflexive, subcortical pathway, likely involving the superior colliculus, and does not require attention. Therefore, EVR may help guide movements toward neglected space. Additionally, presenting stimuli from the neglected (left) field into the attended (right) field, or using specific colors and illustrations processed via non-attentional visual pathways, may further enhance responses. This study tests whether combining EVR, visuospatial shifts, and visual features can effectively facilitate reactions toward the neglected space. Basic objectives2 - Efficacy

Eligibility: Age-lower limit - 18 years-old = Gender - Male and Female Key inclusion criteria - [Stroke Patients] - Inpatients or outpatients with stroke. - Individuals clinically reported to show symptoms of unilateral spatial neglect. Key exclusion criteria - [Healthy participants] - No history of neurological disorders. - No visual problems such as diplopia (including visual field defects).

[Stroke patients] - No history of neurological disorders other than stroke. - Able to understand the experimental tasks. - No visual problems such as diplopia (including visual field defects). Target Size - 80

Recruitment Status: Recruitment status - Enrolling by invitation Date of protocol fixation - 2024 Year 10 Month 01 Day Date of IRB - 2024 Year 06 Month 10 Day Anticipated trial start date - 2024 Year 10 Month 01 Day Last follow-up date - 2029 Year 05 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000067949

Disclaimer: Curated by HT Syndication.