Tokyo, Dec. 26 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060069) titled 'Construction of a Large-Scale Database for Machine Learning in Brain Imaging' on Dec. 26.

Study Type: Others,meta-analysis etc

Primary Sponsor: Institute - Keio University

Condition: Condition - Mental Disorders and Healthy Controls Classification by malignancy - Others Genomic information - YES

Objective: Narrative objectives1 - Purpose of this research: In this research, we will collect MRI images from an open dataset and process them using a common preprocessing pipeline to create a database for secondary machine learning of brain images. Using the collected image data, we will create a standard model based on labels that are expected to be minimally attached to the image data, such as age and gender. By performing transfer learning based on this standard model, we aim to reduce the effort (time, manpower, and funds) required to create large amounts of labeled data for model creation, and to use transfer learning to create highly accurate models for problems where obtaining large amounts of labeled brain images is clinically difficult. Significance of this research: If this research creates a database for secondary brain image machine learning, it will solve a fundamental problem associated with creating AI for brain images (the effort (time, manpower, and funds) required to create large amounts of labeled data). Furthermore, transfer learning will enable the creation of highly accurate models for problems where obtaining large amounts of labeled brain images is clinically difficult. Basic objectives2 - Safety,Efficacy

Eligibility: Age-lower limit - 18 years-old = Gender - Male and Female Key inclusion criteria - Inclusion Criteria 1. MRI brain images are available. 2. Information regarding age or sex is available. Include cases that meet the above inclusion criteria. Include cases with available MRI brain images and age/sex information necessary for creating a baseline model based on age and sex. Key exclusion criteria - Participation in the study will be discontinued for a subject if any of the following criteria apply: 1) The subject requests to withdraw from the study or withdraws consent. 2) Ineligibility is determined after enrollment. 3) A major violation of the study protocol is identified. 4) Other circumstances deemed necessary by the Principal Investigator or Co-Investigator [Withdrawal Procedure] (a) Patients withdrawn from the study will not undergo further evaluations for the study. (b) There are no plans to add additional cases due to early withdrawal of research subjects.

Recruitment Status: Recruitment status - Enrolling by invitation Date of protocol fixation - 2022 Year 03 Month 10 Day Date of IRB - 2022 Year 03 Month 10 Day Anticipated trial start date - 2022 Year 04 Month 01 Day Last follow-up date - 2028 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068690

Disclaimer: Curated by HT Syndication.