Tokyo, Jan. 11 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060317) titled 'Effect of continuous ingestion of yogurt fermented with OLL1073R-1 and OLS3059 strains on salivary IgA antibody secretion' on Jan. 10.
Study Type:
Interventional
Study Design:
Basic Design - Cross-over
Randomization - Randomized
Blinding - Open -but assessor(s) are blinded
Control - No treatment
Primary Sponsor:
Institute - Waseda University
Condition:
Condition - N/A
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - The main purpose of this study is to obtain knowledge about the effect of ingestion of yogurt (Meiji Probio Yogurt R-1) fermented with Lactobacillus delbruekii subsp. bulgaricus OLL1073R-1 (hereinafter referred to as OLL1073R-1 strain) and Streptococcus thermophilus OLS3059 (hereinafter referred to as OLS3059 strain) on salivary s-IgA antibody secretion in young athletes. Moreover, a secondary objective of this study is to confirm the effects on body composition, body temperature, salivary cortisol concentration, and the health-related QOL scale (SF-8).
Basic objectives2 - Efficacy
Intervention:
Interventions/Control_1 - Intake of yogurt (Meiji Probio Yogurt R-1) fermented with Lactobacillus delbruekii subsp. bulgaricus OLL1073R-1 (OLL1073R-1 strain) and Streptococcus thermophilus OLS3059 (OLS3059 strain) was performed daily at a dose of 112g/day for 8 weeks.
Interventions/Control_2 - Eight weeks of normal living without yogurt.
Eligibility:
Age-lower limit - 18
years-old
=
Gender - Male
Key inclusion criteria - Waseda University Rugby Football Club players
Key exclusion criteria - Those with dairy allergies, lactose intolerance, or Sjogren's syndrome
Target Size - 50
Recruitment Status:
Recruitment status - Preinitiation
Date of protocol fixation - 2026 Year 01 Month 10 Day
Anticipated trial start date - 2026 Year 01 Month 23 Day
Last follow-up date - 2028 Year 03 Month 31 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068405
Disclaimer: Curated by HT Syndication.
