Tokyo, June 24 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062032) titled 'Effect of Vitamin C Supplementation at Lunch on Premenstrual Syndrome' on June 23.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Randomized Blinding - Single blind -participants are blinded Control - Placebo

Primary Sponsor: Institute - Hiroshima University

Condition: Condition - Premenstrual Syndrome Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - This study aims to investigate the effects of vitamin C supplementation at lunch on premenstrual syndrome (PMS) symptoms in women with PMS. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - Vitamin C supplementation Interventions/Control_2 - Placebo

Eligibility: Age-lower limit - 18 years-old = Gender - Female Key inclusion criteria - Females aged 18 to 39 years. Regular menstrual cycles (25 to 38 days). Presence of premenstrual syndrome. Habitual breakfast consumption. No current use of vitamin C containing supplements. Availability to participate throughout the study period and attend scheduled laboratory visits. Ability to download and use the designated smartphone application. Key exclusion criteria - Highly irregular daily schedules (including night-shift or rotating shift work). History of gynecological disorders (e.g., ovarian cysts, uterine fibroids, or reproductive malignancies). History of severe psychiatric disorders (e.g., schizophrenia, bipolar disorder, anxiety disorders, or depression). Current use of sex hormone therapies or anti-hormonal treatments. Dietary restrictions or medical nutrition therapy. Regular use of sleep medications or sleep-promoting supplements. Allergy to any ingredients of the study supplement. Planned travel across time zones exceeding 2 hours during the study period. Deemed unsuitable for participation by the investigators. Target Size - 40

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2026 Year 06 Month 15 Day Date of IRB - 2026 Year 06 Month 15 Day Anticipated trial start date - 2026 Year 06 Month 23 Day Last follow-up date - 2026 Year 10 Month 30 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000070982

Disclaimer: Curated by HT Syndication.