Tokyo, Jan. 21 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060417) titled 'Effects of a low-load, bone-focused exercise (OSTEO) program on bone properties in older women' on Jan. 21.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Randomized Blinding - Open -no one is blinded Control - No treatment

Primary Sponsor: Institute - Hiroshima University

Condition: Condition - Age-related bone loss (risk of osteoporosis) Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The purpose of the present study was to investigate the effects of a 12-week OSTEO program on bone mineral density of the femoral neck and lumbar spine assessed by dual-energy X-ray absorptiometry, as well as to evaluate changes in calcaneal quantitative ultrasound parameters, in community-dwelling postmenopausal women. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - Participants in the intervention group performed a low-load, bone-focused exercise program (OSTEO) for 12 weeks. Sessions were held once weekly for 60 minutes under the supervision of trained instructors. Each session consisted of a 45-minute seated component (three 15-minute blocks) and a 15-minute standing component. The seated component sequentially focused on (1) the feet and lower limb alignment, (2) the knees, hips, and lumbar spine, and (3) the ribs and shoulder girdle. The standing component emphasized whole-body skeletal integration centered on the spine and was performed with rhythmic music. Exercise intensity was set using the Borg 6-20 Rating of Perceived Exertion scale: 9-12 for seated exercises and 12-14 for standing exercises. All exercises were performed barefoot, and attendance was recorded for each session. Interventions/Control_2 - Participants in the control group received no specific exercise intervention and were instructed to maintain their usual daily activities during the study period.

Eligibility: Age-lower limit - 68 years-old = Gender - Female Key inclusion criteria - Community-dwelling older women who were able to perform activities of daily living independently and provided written informed consent to participate in the study. Key exclusion criteria - Individuals with medical conditions or treatments known to substantially affect bone metabolism, or those with contraindications to exercise identified during medical screening. Target Size - 22

Recruitment Status: Recruitment status - No longer recruiting Date of protocol fixation - 2025 Year 11 Month 28 Day Date of IRB - 2025 Year 11 Month 27 Day Anticipated trial start date - 2025 Year 12 Month 01 Day Last follow-up date - 2026 Year 02 Month 28 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000069106

Disclaimer: Curated by HT Syndication.