Tokyo, Sept. 2 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000058955) titled 'Effects of combined cognitive training and comprehensive cardiac rehabilitation on mild cognitive impairment in older patients with heart failure' on Sept. 1.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Randomized Blinding - Open -no one is blinded Control - Active

Primary Sponsor: Institute - Konan Women's University

Condition: Condition - Heart failure Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - To investigate the effects of combined cognitive training and comprehensive cardiac rehabilitation on mild cognitive impairment in older patients with heart failure Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - 1) Usual care 2) Exercise therapy (20-40 minutes per day, 5 days per week) 3) Cognitive training (20 minutes per day, 5 days per week) 4) Diet therapy, Disease management counseling, Vascular risk monitoring Interventions/Control_2 - 1) Usual care 2) Exercise therapy (20-40 minutes per day, 5 days per week) 3) Diet therapy, Disease management counseling, Vascular risk monitoring

Eligibility: Age-lower limit - 65 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - 1) Patients who were hospitalized for heart failure and conducted rehabilitation 2) Aged 65 years or older 3) Patient who were mild cognitive impairment (Japanese version of the Montreal Cognitive Assessment: 17-22 points) Key exclusion criteria - 1) Patients whose consent was not obtained 2) Acute coronary syndrome 3) Severe symptomatic aortic stenosis, mitral stenosis, and hypertrophic obstructive cardiomyopathy 4) Patients undergoing hemodialysis 5) Requiring high inotropic support 6) Patients with circulatory assist device 7) Short life expectancy due to advanced disease other than heart failure 8) Patients who could not walk without total assistance Target Size - 100

Recruitment Status: Recruitment status - Enrolling by invitation Date of protocol fixation - 2025 Year 08 Month 31 Day Date of IRB - 2025 Year 08 Month 06 Day Anticipated trial start date - 2025 Year 09 Month 01 Day Last follow-up date - 2027 Year 12 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000067410

Disclaimer: Curated by HT Syndication.