Tokyo, Nov. 15 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000059786) titled 'Effects of consumption of the test food on bowel movements and gut microbiome' on Nov. 14.
Study Type:
Interventional
Study Design:
Basic Design - Parallel
Randomization - Randomized
Blinding - Double blind -all involved are blinded
Control - Placebo
Primary Sponsor:
Institute - Euglena Co., Ltd.
Condition:
Condition - Healthy Japanese
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - To verify the effects of consumption of the test food on bowel movements and gut microbiome.
Basic objectives2 - Efficacy
Intervention:
Interventions/Control_1 - Duration: Four weeks
Test product: Test food
Administration: Three capsules/pack/day
Interventions/Control_2 - Duration: Four weeks
Test product: Placebo food
Administration: Three capsules/pack/day
Eligibility:
Age-lower limit - 18
years-old
<=
Age-upper limit - Not applicable
Gender - Male and Female
Key inclusion criteria - 1. Japanese
2. Men or women
3. Adults
4. Healthy participants
5. Participants with 3 to 5 bowel movements per day during any period in Screening Tests 1 and 2
Key exclusion criteria - Participants who
1. are undergoing medical treatment or have a medical history of malignant tumor, heart failure, or myocardial infarction
2. have a pacemaker or an implantable cardioverter defibrillator (ICD)
3. are currently undergoing treatment for any of the following chronic diseases: cardiac arrhythmia, liver disorder, chronic kidney disease, cerebrovascular disorder, rheumatic disease, diabetes mellitus, dyslipidemia, hypertension, or any other chronic diseases
4. are taking "Foods for Specified Health Uses" or "Foods with Functional Claims"
5. are taking or using medicines (including herbal medicines) or supplements
6. regularly and intentionally consume medicines, health supplements, Foods for Specified Health Uses, Foods with Functional Claims, or foods fortified with ingredients that may affect bowel movements (e.g., fermented foods such as natto, kimchi, and pickles; foods fortified with dietary fiber; and dairy products such as yogurt, fermented milk, and cheese)
7. currently smoke or have quit smoking within one year prior to providing consent for this study
8. drink alcoholic beverages excessively
9. are on a diet or engage in strenuous exercise for the purpose of physical strengthening
10. have an irregular lifestyle due to shift work or other reasons
11. are taking anticoagulants such as warfarin
12. have extreme eating habits (e.g., strict vegetarianism, consuming only junk food, or always eating the same set menu)
13. are allergic to medicines or foods related to the test product
14. are pregnant, lactating, or planning to become pregnant during this study
15. have been enrolled in other clinical studies within the last 28 days before the agreement to participate in this study or plan to participate in another study during this study
16. are judged as ineligible to participate in this study by the physician
Target Size - 100
Recruitment Status:
Recruitment status - Open public recruiting
Date of protocol fixation - 2025 Year 11 Month 12 Day
Date of IRB - 2025 Year 11 Month 12 Day
Anticipated trial start date - 2025 Year 11 Month 14 Day
Last follow-up date - 2026 Year 05 Month 01 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068360
Disclaimer: Curated by HT Syndication.