Tokyo, Jan. 9 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060305) titled 'Effects of consumption of the test food on cognitive function in healthy Japanese' on Jan. 8.
Study Type:
Interventional
Study Design:
Basic Design - Parallel
Randomization - Randomized
Blinding - Double blind -all involved are blinded
Control - Placebo
Primary Sponsor:
Institute - OSAKA SODA CO., LTD.
Condition:
Condition - Healthy Japanese
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - To verify the effects of consumption of the test food on cognitive function in healthy Japanese.
Basic objectives2 - Safety,Efficacy
Intervention:
Interventions/Control_1 - Duration: 12 weeks
Test product: Lactic acid bacteria-containing food
Administration: Consume one tablet per day in the morning.
*If a dose is missed, it should be consumed as soon as remembered. The daily dose should be consumed within the same day and should not be carried over to the following day.
Interventions/Control_2 - Duration: 12 weeks
Test product: Placebo food
Administration: Consume one tablet per day in the morning.
*If a dose is missed, it should be consumed as soon as remembered. The daily dose should be consumed within the same day and should not be carried over to the following day.
Eligibility:
Age-lower limit - 40
years-old
<=
Age-upper limit - Not applicable
Gender - Male and Female
Key inclusion criteria - 1. Japanese
2. Men or women
3. Individuals aged 40 or more
4. Healthy individuals
5. Individuals whose Mini-Mental State Examination (MMSE) score is 24 or higher at screening
6. Individuals whose validity indicator for the Visual Memory test of Cognitrax is "yes" at screening
7. Individuals whose standardized score for Visual Memory in Cognitrax is 99 or lower at screening
Key exclusion criteria - 1. Individuals who are undergoing medical treatment or have a medical history of malignant tumor, heart failure, or myocardial infarction
2. Individuals who have a pacemaker or an implantable cardioverter defibrillator (ICD)
3. Individuals who are currently undergoing treatment for any of the following chronic diseases: cardiac arrhythmia, liver disorder, chronic kidney disease, cerebrovascular disorder, rheumatic disease, diabetes mellitus, dyslipidemia, hypertension, or any other chronic diseases
4. Individuals who are taking "Foods for Specified Health Uses" or "Foods with Functional Claims"
5. Individuals who are taking or using medications (including herbal medicines) or supplements
6. Individuals who are allergic to medicines or foods related to the test product
7. Individuals who are pregnant, lactating, or planning to become pregnant during this study
8. Individuals who have been enrolled in other clinical studies within the last 28 days before the agreement to participate in this study or plan to participate in another study during this study
9. Individuals who usually take supplements or foods that may be related to improving cognitive functions, such as docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), ginkgo leaf extract, tocotrienol, astaxanthin, gamma-aminobutyric acid (GABA), phosphatidylserine, and plasmalogen
10. Individuals who use devices, equipment, and applications that may affect cognitive functions (such as brain training puzzles or games) in daily
11. Individuals who are judged as ineligible to participate in this study by the physician
Target Size - 38
Recruitment Status:
Recruitment status - Open public recruiting
Date of protocol fixation - 2025 Year 12 Month 10 Day
Date of IRB - 2025 Year 12 Month 10 Day
Anticipated trial start date - 2026 Year 01 Month 08 Day
Last follow-up date - 2026 Year 07 Month 16 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068977
Disclaimer: Curated by HT Syndication.