Tokyo, April 8 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061191) titled 'Effects of different resistance training modalities on muscle strength gains and urinary titin concentration dynamics' on April 7.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Randomized Blinding - Open -no one is blinded Control - Dose comparison

Primary Sponsor: Institute - Iwate Medical University

Condition: Condition - Healthy adults Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The purpose of this study is to compare the effects of different combinations of training intensity and frequency on quadriceps muscle strength, muscle thickness, skeletal muscle mass, and urinary titin concentration following an 8-week resistance training (RT) program, aiming to determine the optimal exercise dose for effective muscle strengthening. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - High-intensity, high-frequency group(Resistance training at 80% of 1RM, 3 times per week) Interventions/Control_2 - High-intensity, low-frequency group(Resistance training at 80% of 1RM, 1 time per week)

Eligibility: Age-lower limit - 20 years-old = Gender - Male Key inclusion criteria - 1) Healthy male adults aged 20 to 39 years 2) Individuals without a regular exercise habit Key exclusion criteria - 1) Individuals with symptoms such as pain or numbness in the lower extremities 2) Individuals with a history of musculoskeletal disorders in the lower extremities within the past 6 months 3) Individuals judged to have difficulty continuing the exercise program in this study Target Size - 80

Recruitment Status: Recruitment status - Completed Date of protocol fixation - 2023 Year 09 Month 01 Day Date of IRB - 2023 Year 09 Month 01 Day Anticipated trial start date - 2023 Year 09 Month 07 Day Last follow-up date - 2023 Year 12 Month 26 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000070023

Disclaimer: Curated by HT Syndication.