Tokyo, Nov. 5 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000059634) titled 'Effects of Hinoki (Japanese cypress) essential oil olfactory stimulation on prefrontal cortex activity and autonomic nervous activity: a crossover trial' on Nov. 4.
Study Type:
Interventional
Study Design:
Basic Design - Cross-over
Randomization - Randomized
Blinding - Open -no one is blinded
Control - Placebo
Primary Sponsor:
Institute - Chiba University
Condition:
Condition - Healthy person
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - This study aims to elucidate the effects of olfactory stimulation with essential oil extracted from Hinoki (Japanese cypress) wood on prefrontal cortex activity and autonomic nervous activity in healthy Japanese university and graduate students aged 20-29.
Basic objectives2 - Efficacy
Intervention:
Interventions/Control_1 - Olfactory stimulation with essential oil extracted from Japanese cypress (Hinoki) wood (90 s) -> Rest period -> Control: No odor (air, 90 s)
Interventions/Control_2 - Control: No odor (air, 90 s) -> Rest period -> Olfactory stimulation with essential oil extracted from Japanese cypress (Hinoki) wood (90 s)
Eligibility:
Age-lower limit - 20
years-old
Gender - Male and Female
Key inclusion criteria - Healthy person
Key exclusion criteria - 1) History of allergy to Hinoki (Japanese cypress) wood or Hinoki essential oil.
2) Respiratory conditions such as asthma, chronic rhinitis, or seasonal allergic rhinitis (hay fever), by self-report or prior physician diagnosis.
3) Currently receiving treatment for any disease at a medical institution.
4) Current smoking habit.
5) History or diagnosis of cardiac arrhythmia.
6) Menstruation on the test day (female participants only).
Target Size - 80
Recruitment Status:
Recruitment status - Preinitiation
Date of protocol fixation - 2025 Year 09 Month 19 Day
Date of IRB - 2025 Year 10 Month 30 Day
Anticipated trial start date - 2025 Year 11 Month 04 Day
Last follow-up date - 2026 Year 01 Month 31 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068212
Disclaimer: Curated by HT Syndication.
