Tokyo, April 8 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061190) titled 'Efficacy of Oral Care with MA-T in Preventing Ventilator-Associated Pneumonia in Intubated ICU Patients' on April 7.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Non-randomized Blinding - Open -no one is blinded Control - Active

Primary Sponsor: Institute - Tokyo Science University Hospital

Condition: Condition - Intubated patients in the intensive care unit Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - To investigate whether oral care using MA-T reduces the incidence of ventilator-associated pneumonia (VAP) compared with conventional oral care in intubated patients admitted to the ICU Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - Oral care with conventional oral care kit mouthwash (6 ml) and mouth paste (2 g) for brushing. Interventions/Control_2 - Oral care using MA-T mouthwash (6 ml) and MA-T oral gel (2 g) for brushing, in place of conventional mouthwash and mouth paste.

Eligibility: Age-lower limit - 18 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - Patients intubated and receiving mechanical ventilation Key exclusion criteria - Patients extubated within 48 hours of intubation Patients with oral or facial trauma Patients at risk of oral bleeding due to coagulopathy, oral ulcers, or other conditions that may be exacerbated by frequent oral care Patients capable of performing oral care independently Patients with pneumonia as the primary diagnosis at admission Target Size - 200

Recruitment Status: Recruitment status - Open public recruiting Date of protocol fixation - 2026 Year 01 Month 27 Day Date of IRB - 2026 Year 01 Month 27 Day Anticipated trial start date - 2026 Year 03 Month 01 Day Last follow-up date - 2028 Year 12 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000070025

Disclaimer: Curated by HT Syndication.