Tokyo, April 1 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060893) titled 'Estimation of Pelvic and Thigh Muscle Volume from Arbitrary Cross-Sections Using MRI' on April 1.

Study Type: Observational

Primary Sponsor: Institute - Ibaraki Prefectural University of Health Sciences

Condition: Condition - Osteoarthritis of the hip Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - In this study, we focus on differences in the geometric morphology of muscles and aim to identify the optimal surrogate cross-section that shows the highest correlation with total muscle volume using multiplanar reconstruction (MPR) images generated from MRI data. Specifically, the gluteal muscles (gluteus maximus, gluteus medius, and gluteus minimus) will be analyzed as representative radial muscles, while the thigh muscles (e.g., quadriceps femoris and hamstrings) will be analyzed as representative fusiform muscles. Instead of limiting the analysis to conventional axial cross-sections, multiple candidate planes aligned with the muscle fiber direction will be generated. By evaluating how different combinations of plane position and orientation affect the accuracy of muscle volume estimation, the optimal surrogate cross-section for each muscle morphology will be determined. Basic objectives2 - Safety,Efficacy

Eligibility: Age-lower limit - 18 years-old

Gender - Male and Female Key inclusion criteria - healthy adults (over 18 years old) Key exclusion criteria - Individuals with a history of pelvic or thigh surgery Individuals with underlying diseases such as hypertension or diabetes that may make it difficult to remain still during the examination Individuals who are pregnant or may be pregnant Individuals with metallic implants (e.g., cardiac pacemakers or ferromagnetic implants) Individuals judged to be unsuitable for participation by the principal investigator (e.g., tattoos, cosmetic tattoos, or claustrophobia) Target Size - 20

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2026 Year 04 Month 01 Day Anticipated trial start date - 2026 Year 04 Month 01 Day Last follow-up date - 2029 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000069686

Disclaimer: Curated by HT Syndication.