Tokyo, Jan. 25 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060456) titled 'Evaluation of the Effects of Combined 5G Radiofrequency Exposure on Human Skin' on Jan. 24.

Study Type: Interventional

Study Design: Basic Design - Cross-over Randomization - Non-randomized Blinding - Single blind -participants are blinded Control - Placebo

Primary Sponsor: Institute - Kurume University

Condition: Condition - None (healthy volunteers only) Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - This study aims to characterize the physiological responses of human skin to radiofrequency exposure at 28 GHz and 2 GHz, focusing on changes in skin temperature, skin blood flow, thermal sensation, and stress-related biomarkers. In addition, the study seeks to clarify whether simultaneous exposure to multiple frequencies produces physiological responses that differ from those induced by single-frequency exposure, thereby providing biological evidence to support the scientific basis of international radiofrequency exposure guidelines. Basic objectives2 - Others

Intervention: Interventions/Control_1 - 28 GHz Single-Frequency Exposure : To evaluate the effects of single-frequency exposure to 28 GHz millimeter-wave radiation on human skin by assessing changes in skin surface temperature, skin blood flow, thermal sensation, and stress-related biomarkers. Interventions/Control_2 - 2 GHz Single-Frequency Exposure : To evaluate the effects of single-frequency exposure to 2 GHz radiofrequency fields on human skin by assessing changes in skin surface temperature, skin blood flow, thermal sensation, and stress-related biomarkers.

Eligibility: Age-lower limit - 18 years-old = Gender - Male and Female Key inclusion criteria - Participants must meet all of the following criteria: 1. Adults aged between 18 and 79 years at the time of obtaining informed consent. 2. Healthy individuals. 3. Individuals who have received sufficient explanation of the purpose and procedures of the study and have provided written informed consent. 4. Individuals who are able to undergo radiofrequency exposure, skin temperature measurement, skin blood flow measurement, and thermal sensation assessment as specified in the study protocol. Key exclusion criteria - Participants meeting any of the following criteria will be excluded from the study: 1. Individuals with skin conditions at the measurement site (dorsal skin) that would make the planned measurements or assessments difficult to perform at the time of the study. 2. Individuals who are judged by the principal investigator or study investigators to be inappropriate for participation in the study. Target Size - 20

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2025 Year 11 Month 05 Day Anticipated trial start date - 2026 Year 01 Month 26 Day Last follow-up date - 2029 Year 03 Month 03 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000069174

Disclaimer: Curated by HT Syndication.