Tokyo, Aug. 15 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062425) titled 'Evaluation of the relationship between oral microbiota and daily habits in terms of diet and oral cleaning' on Aug. 10.

Study Type: Interventional

Study Design: Basic Design - Single arm Randomization - Non-randomized Blinding - Open -no one is blinded Control - Uncontrolled

Primary Sponsor: Institute - National Institute of Advanced Industrial Science And Technology(AIST)

Condition: Condition - Healthy subjects Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - Recently, the influence of the oral microbiota not only on oral diseases but also on systemic diseases has been focused. While the oral microflora is reported to be diverse from individual to individual, the factors that influence the diversity are yet to be elucidated. In addition, most studies on oral microflora have focused on saliva and dental plaque samples, and there have been few studies specifically on the tongue coating. In this research project, we will collect oral bacteria from tongue coating and analyze the composition and diversity of the oral microflora of individual subjects by next-generation sequencing analysis, and 1. clarify the dietary habit factors that influence the diversity by using the BDHQ dietary habit questionnaire survey. 2. clarify whether the diversity of oral microflora is changed by the intervention of tongue cleaning as an oral cleaning habit. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - Daily Tongue blushing once a day for 10 days

Eligibility: Age-lower limit - 20 years-old = Gender - Male and Female Key inclusion criteria - People who are able to obtain written consent to participate in the research from the individual by their own will Key exclusion criteria - 1.People who are scheduled for dental treatment during the study period 2.People who need to take antibiotics one month prior to the study period and during the study period 3.Denture wearers 4.People who habitually clean their tongue 5.Smorkers 6.Pregnant woman 7.People with a vomiting reflex and difficulty contacting the tongue Target Size - 40

Recruitment Status: Recruitment status - No longer recruiting Date of protocol fixation - 2024 Year 06 Month 01 Day Date of IRB - 2024 Year 08 Month 20 Day Anticipated trial start date - 2024 Year 10 Month 23 Day Last follow-up date - 2027 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000062661

Disclaimer: Curated by HT Syndication.