Tokyo, Oct. 5 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000063166) titled 'Feasibility Study of Pulse Wave-Like Signal Measurement in Healthy Adults Using an Ultrasound Sensor System' on Oct. 5.

Study Type: Interventional

Study Design: Basic Design - Single arm Randomization - Non-randomized Blinding - Open -no one is blinded Control - Uncontrolled

Primary Sponsor: Institute - Tohoku university

Condition: Condition - healthy adults Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - This exploratory study will assess noninvasive pulse waveform acquisition using an ultrasound sensor system under development in healthy adults. At the radial artery, two-site PWV will be assessed at rest, during leg elevation, and during deep breathing, and compared with changes in systolic blood pressure. At rest, waveforms from both common carotid arteries will be acquired and compared. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - Several minutes of lower limb elevation/Several deep breaths

Eligibility: Age-lower limit - 18 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - (1) Individuals aged 18 years or older at the time of enrollment (2) Individuals who self-report that they have not been diagnosed by a physician with hypertension, cardiovascular disease, cerebrovascular disease, or respiratory disease that may affect their ability to perform deep breathing (3) Individuals who are able to perform deep breathing and lower limb elevation without assistance (4) Individuals who have provided written informed consent to participate in the study Key exclusion criteria - (1) Individuals with a resting systolic blood pressure of 140 mmHg or higher or a resting diastolic blood pressure of 90 mmHg or higher before the start of measurement (2) Individuals with wounds, inflammation, infection, or other skin conditions on the forearm or neck where the sensors and fixation devices will be placed (3) Individuals with an allergy to polyurethane gel or a history of itching or redness associated with the use of ultrasound gel (4) Individuals who are pregnant or who self-report the possibility of pregnancy Target Size - 12

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2026 Year 09 Month 25 Day Anticipated trial start date - 2026 Year 11 Month 01 Day Last follow-up date - 2027 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000072283

Disclaimer: Curated by HT Syndication.