Tokyo, April 9 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061203) titled 'Follitropin Beta vs Follitropin Delta for Poor Responders to Rekovelle: A Preliminary Comparison' on April 8.
Study Type:
Observational
Primary Sponsor:
Institute - Haruki Ladies Clinic
Condition:
Condition - infertility
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - To investigate whether switching from follitropin delta to follitropin beta improves the number of oocytes retrieved and the number of blastocysts obtained in cases that showed a poor response to ovarian stimulation with follitropin delta.
Basic objectives2 - Efficacy
Eligibility:
Age-lower limit - 20
years-old
=
Gender - Female
Key inclusion criteria - Female patients who underwent in vitro fertilization and embryo transfer at our clinic
Having undergone at least one ovarian stimulation cycle using follitropin delta (Rekovelle) with an antagonist protocol
Having undergone at least one subsequent cycle switched to follitropin beta (Follitropin) with an antagonist protocol due to poor response to follitropin delta
Oocyte retrieval date between January 1, 2025 and March 31, 2026
Key exclusion criteria - Cycles in which other gonadotropin preparations were added during follitropin delta stimulation
Cycles using stimulation protocols other than the antagonist protocol (e.g., PPOS)
Patients with a history of ovarian surgery that may have affected ovarian reserve
Cycles in which the stimulation protocol was modified for OHSS prevention
Cycles with missing data precluding analysis of the primary outcome
Target Size - 50
Recruitment Status:
Recruitment status - Preinitiation
Date of protocol fixation - 2026 Year 04 Month 08 Day
Anticipated trial start date - 2026 Year 04 Month 08 Day
Last follow-up date - 2026 Year 04 Month 30 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000070029
Disclaimer: Curated by HT Syndication.
