Tokyo, Feb. 18 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060693) titled 'Frequency and Intake Study after Post-Egg Oral Food Challenge' on Feb. 17.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Randomized Blinding - Open -no one is blinded Control - Active

Primary Sponsor: Institute - NHO Sagamihara National Hospital

Condition: Condition - Food allergy Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - To compare the efficacy of frequent low-dose versus standard-dose home intake of heated egg by evaluating symptom occurrence at 1/2 egg OFC after 6 months in children who tested negative for 1/8 egg OFC. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - Tamakona(R) 250 three times per week for 6 months. Interventions/Control_2 - Tamakona(R) 750 once per week for 6 months.

Eligibility: Age-lower limit - Not applicable Age-upper limit - 18 years-old >= Gender - Male and Female Key inclusion criteria - Patients with a history of immediate-type allergic reactions to hen's egg Patients who had a negative oral food challenge (OFC) to 1/8 of a heated hen's egg at our hospital OR Patients who had a positive OFC to 1/2 of a heated whole egg at our hospital Patients (or their guardians) who provided written informed consent for participation in the study Key exclusion criteria - Patients with severe comorbidities (e.g., severe asthma, cardiac disease) Patients scheduled to receive other allergy treatments (e.g., oral immunotherapy) during the study period Patients deemed inappropriate for study participation by the principal investigator Target Size - 104

Recruitment Status: Recruitment status - Open public recruiting Date of protocol fixation - 2025 Year 03 Month 28 Day Date of IRB - 2025 Year 03 Month 28 Day Anticipated trial start date - 2026 Year 02 Month 17 Day Last follow-up date - 2030 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000069423

Disclaimer: Curated by HT Syndication.