Tokyo, May 13 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061543) titled 'Genome-wide serum microRNA profiling before and after sleeve gastrectomy: a pilot study comparing metabolically healthy and metabolically unhealthy obesity' on May 13.
Study Type:
Observational
Primary Sponsor:
Institute - Ohama Daiichi Hospital
Condition:
Condition - Severe obesity
Classification by malignancy - Others
Genomic information - YES
Objective:
Narrative objectives1 - To comprehensively analyse serum microRNA expression profiles before and after sleeve gastrectomy in patients with severe obesity, and to identify phenotype-specific miRNA expression patterns and candidate biomarkers predictive of post-operative metabolic improvement in metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUO).
Basic objectives2 - Others
Eligibility:
Age-lower limit - 18
years-old
=
Gender - Male and Female
Key inclusion criteria - Patients diagnosed with morbid obesity at our institution between 08/2020and 03/2021
Patients aged 18 years or older
Availability of relevant clinical information from medical records
Informed consent (or opt-out) obtained from patients or their legal representatives
Key exclusion criteria - Cases with poor sample quality unsuitable for analysis
Cases with insufficient clinical information
Cases who declined participation (opted out)
(Relevant comorbidities, e.g., concurrent malignancies, etc.)
Target Size - 8
Recruitment Status:
Recruitment status - Completed
Date of protocol fixation - 2020 Year 04 Month 10 Day
Date of IRB - 2020 Year 07 Month 07 Day
Anticipated trial start date - 2020 Year 08 Month 18 Day
Last follow-up date - 2021 Year 03 Month 31 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000070425
Disclaimer: Curated by HT Syndication.
